References |
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The following includes selected links and publications describing applications of the pZ Expression System in various fields of basic and applied research. A complete reference list can be found here. Weblinks Tetracycline-dependent gene regulation architectures in bacteria (University of Tuebingen) Quantitative control and analysis of gene activities C. C. Guet, L. Bruneaux, T. L. Min, D. Siegal-Gaskins, I. Figueroa, T. Emonet, P. Cluzel. Minimally invasive determination of mRNA concentration in single living bacteria. Nucleic Acids Res (2008), 36(12), e73 (link) S. Da Re, B. Le Quéré, J.-M. Ghigo, C Beloin. Tight Modulation of Escherichia coli Bacterial Biofilm Formation through Controlled Expression of Adhesion Factors. Applied and Environmental Microbiology (2007), 73, 10, 3391-3403. (link) J. H. Urban, J. Vogel. Translational control and target recognition by Escherichia coli small RNAs in vivo. Nucleic Acids Res (2007), 35, 1018-1037. (link) T. T. Le, T. Emonet, S. Harlepp, C. C. Guet, P. Cluzel. Dynamical Determinants of Drug-Inducible Gene Expression in a Single Bacterium. Biophys. J. (2006), 90, 9, 3315 - 3321. (link) T. T. Le, S. Harlepp, C. C. Guet, K. Dittmar, T. Emonet, T. Pan, P. Cluzel. Real-time RNA profiling within a single bacterium. Proc. Natl. Acad. Sci. USA (2005), 102, 26, 9160-9164. (link) L. You, R.S. Cox, R. Weiss, F.H. Arnold. Programmed population control by cell-cell communication and regulated killing. Nature (2004) 428, 868-871 (link) I. Golding, E. C. Cox. RNA dynamics in live Escherichia coli cells. Proc. Natl. Acad. Sci. USA (2004), 101, 31, 11310-11315. (link) M. B. Elowitz, A. J. Levine, E. D. Siggia, P. S. Swain. Stochastic Gene Expression in a Single Cell. Science (2002), 297, 5584, 1183-1186. (link) Independent control of gene activities L. M. Chubiz, C. V. Rao. Computational design of orthogonal ribosomes. Nucleic Acids Res (2008), 36(12), 4038-4046. (link) J. Leandroa, C. Nascimentoa, I. Tavares de Almeidaa, P Leandro. Co-expression of different subunits of human phenylalanine hydroxylase: Evidence of negative interallelic complementation. Biochimica et Biophysica Acta (2006), 1762, 5, 544-550 (link) R.B. Kapust, D.S. Waugh. Controlled Intracellular Processing of Fusion Proteins by TEV Protease. Protein Expression and Purification (2000), 19, 2, 312-318 (link) Cloning and Expression of toxic or harmful Gene Products R Rimoleliene, A Janulaitis. Saturation mutagenesis of Thr862, the amino acid essential for substrate specificity of Eco57I restriction endonuclease. Biologija (2005), 1, 11-14 (link) L. You, R. S. Cox, R. Weiss, F. H. Arnold. Programmed population control by cell–cell communication and regulated killing. Nature (2004), 428, 868-871. (link) A. Grundling, M.D. Manson, R. Young. Holins kill without warning. Proc. Natl. Acad. Sci. USA (2001), 98, 16, 9348-9352. (link) R. Lutz, H. Bujard. Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements. Nucleic Acids Res. (1997) 25, 6, 1203-1210 (link) Screening A. Hsiao, Z. Liu, A. Joelsson, J. Zhu. Vibrio cholerae virulence regulator-coordinated evasion of host immunity. Proc. Natl. Acad. Sci. USA (2006), 103, 39, 14542-14547. (link) K. Jensen, H. Alper, C. Fischer, G. Stephanopoulos. Identifying Functionally Important Mutations from Phenotypically Diverse Sequence Data. Applied and Environmental Microbiology (2006), 72, 5, 3696-3701. (link) K. Jensen, H. Alper, C. Fischer, G. Stephanopoulos. Identifying Functionally Important Mutations from Phenotypically Diverse Sequence Data. Appl. Env. Biol. (2006), 72, 5, 3696-3701. (link) S. Cabantous, T.C. Terwilliger, G.S. Waldo. Protein tagging and detection with engineered self-assembling fragments of green fluorescent protein. Nature Biotech. (2005), 23, 1, 102-107. (link) X.-X. Tan & Y. Chen. A Novel Genomic Approach Identifies Bacterial DNA-Dependent RNA Polymerase as the Target of an Antibacterial Oligodeoxynucleotide, RBL1. Biochemistry (2005), 44, 17, 6708-6714. (link) X.-X. Tan, K. Rose, W. Margolin, Y. Chen. DNA Enzyme Generated by a Novel Single-Stranded DNA Expression Vector Inhibits Expression of the Essential Bacterial Cell Division Gene ftsZ. Biochemistry (2004), 43, 1111-1117 (link) D. Christ, G. Winter. Identification of functional similarities between proteins using directed evolution. Proc. Nat. Acad. Sci. USA (2003), 100, 23, 13202-13206. (link) Transcriptional Cascades/Genetic Switches M.J.Dunlop, R.S. Cox, J.H. Levine, R.M. Murray, M.B. Elowitz. Regulatory activity revealed by dynamic correlations in gene expression noise. Nature Genetics (2008), 40, 12, 1493-1498. (link) J. Stricker, S. Cookson, M. R. Bennett, W.H. Mather, L. S. Tsimring, J. Hasty. A fast, robust and tunable synthetic gene oscillator. Nature (2008), 456, 7221, 516-519. (link) S. Hooshangi, S. Thiberge, R. Weiss. Ultrasensitivity and noise propagation in a synthetic transcriptional cascade. Proc. Natl. Acad. Sci. USA (2005), 102, 10, 3581-3586. (link) H. Kobayashi, M. Kaern, M. Araki, K. Chung, T. S. Gardner, C. R. Cantor, J. J. Collins. Programmable cells: Interfacing natural and engineered gene networks. Proc. Natl. Acad. Sci. USA (2004), 101, 22, 8414-8419. (link) C. C. Guet, M. B. Elowitz, W. Hsing, S. Leibler. Combinatorial Synthesis of Genetic Networks. Science (2002), 296, 5572, 1466-1470. (link) Overexpression M. Guillier, S. Gottesman. Remodelling of the Escherichia coli outer membrane by two small regulatory RNAs. Mol. Microbiol. (2006), 59 (1), 231-247. (link) K. Zhao, M. Liu, R. R. Burgess. The Global Transcriptional Response of Escherichia coli to Induced Sigma32 Protein Involves Sigma32 Regulon Activation Followed by inactivation and Degradation of Sigma32 in Vivo. J. Biol. Chem. (2005), 280, 18, 17758-17768. (link) S. Cabantous, T.C. Terwilliger, G.S. Waldo. Protein tagging and detection with engineered self-assembling fragments of green fluorescent protein. Nature Biotech. (2005), 23, 1, 102-107. (link) C. W. Kauth, C. Epp, H. Bujard, R. Lutz. The Merozoite Surface Protein 1 Complex of Human Malaria Parasite Plasmodium falciparum: Interactions and arrangements of subunits. J. Biol. Chem. (2003), 278, 25, 22257-22264. (link) Expression in hosts other than E. coli W. W. Lathem, P. A. Price, V. L. Miller, W. E. Goldman. A Plasminogen-Activating Protease Specifically Controls the Development of Primary Pneumonic Plague. Science (2007), 315, 5811, 509-513. (link) A. Hsiao, Z. Liu, A. Joelsson,J. Zhu. Vibrio cholerae virulence regulator-coordinated evasion of host immunity. Proc. Natl. Acad. Sci. USA (2006), 103, 39, 14542-14547. (link) F. Qian, W. Pan. Construction of a tetR-Integrated Salmonella enterica Serovar Typhi CVD908 Strain That Tightly Controls Expression of the Major Merozoite Surface Protein of Plasmodium falciparum for Applications in Human Vaccine Production. Infect. Immun. (2002), 70, 4, 2029-2038. (link) Reviews R. Bertram, W. Hillen. The application of Tet repressor in prokaryotic gene regulation and expression. Microbial Biotechnology (2008), 1 (1), 2-16 (link), F. Saida, M. Uzan, B. Odaert, F. Bontems. Expression of Highly Toxic Genes in E. coli: Special Strategies and Genetic Tools (2006), in: Current Protein and Peptide Science, 7, 1, 47-56(10), Bentham Science Publishers (link) R. McDaniel & R. Weiss. Advances in synthetic biology: on the path from prototypes to applications. Current Opinion in Biotechnology (2005), 16, 476-483 (link) M. Kærn,W. J. Blake, J.J. Collins. The engeneering of gene regulatory networks. Annu. Rev. Biomed. Eng. (2003), 5,179-206 (link) |